NanoInformaTIXDevelopment and Implementation of a Sustainable Modelling Platform for NanoInformatics. |
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This EUROPIAN H2020-project aims the development and implementation of a sustainable modelling platform for NanoInformatics.
The duration of the action will be 50 months s of 1 January 2019.
Experimental studies in Nanosafety, over the last decades, have generated a considerable amount of data on the potential (eco)-toxicity of engineered nanomaterials (ENM) and their physico-chemical characteristics. The challenge is to successfully establish a quantitative relationship between the ENM characteristics and the observed adverse effects. This can be accomplished by applying modern informatics methods on the large existing and emerging good quality Nanosafety data.
NanoInformaTIX aims to develop, validate and implement a sustainable informatics framework, based on modelling of the entire life cycle, for the risk assessment of ENM and for informing safer design of quality products. This Sustainable NanoInformatics Framework (SNF) will be co-implemented with stakeholders to ensure a user-friendly interface for industry, regulators, researchers and civil society, providing cost-effective safety assessment guidance.
NanoInformaTIX will create a sustainable multi-scale modelling framework, integrating different validated NanoInformatics models from: Materials modelling, Exposure modelling, Bio-distribution modelling: Physiologically-Based Pharmacokinetics (PBPK), to Dose-Response modelling: Quantitative-Structure-Activity Relation (QSAR) and Systems Biology modelling to support the prediction of the potential (eco)-toxicity of ENM during each stage of their production.
Click here for more information.
The duration of the action will be 50 months s of 1 January 2019.
Experimental studies in Nanosafety, over the last decades, have generated a considerable amount of data on the potential (eco)-toxicity of engineered nanomaterials (ENM) and their physico-chemical characteristics. The challenge is to successfully establish a quantitative relationship between the ENM characteristics and the observed adverse effects. This can be accomplished by applying modern informatics methods on the large existing and emerging good quality Nanosafety data.
NanoInformaTIX aims to develop, validate and implement a sustainable informatics framework, based on modelling of the entire life cycle, for the risk assessment of ENM and for informing safer design of quality products. This Sustainable NanoInformatics Framework (SNF) will be co-implemented with stakeholders to ensure a user-friendly interface for industry, regulators, researchers and civil society, providing cost-effective safety assessment guidance.
NanoInformaTIX will create a sustainable multi-scale modelling framework, integrating different validated NanoInformatics models from: Materials modelling, Exposure modelling, Bio-distribution modelling: Physiologically-Based Pharmacokinetics (PBPK), to Dose-Response modelling: Quantitative-Structure-Activity Relation (QSAR) and Systems Biology modelling to support the prediction of the potential (eco)-toxicity of ENM during each stage of their production.
Click here for more information.
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